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HeLa cells : ウィキペディア英語版
HeLa

A HeLa cell , also Hela or hela cell, is a cell type in an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line. The line was derived from cervical cancer cells taken on February 8, 1951 from Henrietta Lacks, a patient who died of her cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific — which has led to it contaminating many other cell lines used in research.〔; Note: Some sources report her birthday as August 2, 1920, vice August 1, 1920.〕
The cells from Lacks' tumor were taken without her knowledge or consent by researcher George Gey, who found that they could be kept alive. Before this, cells cultured from other cells would only survive for a few days. Scientists spent more time trying to keep the cells alive than performing actual research on them, but some cells from Lacks' tumor sample behaved differently from others. George Gey was able to isolate one specific cell, multiply it, and start a cell line. Gey named the sample HeLa, after the initial letters of Henrietta Lacks' name. They were the first human cells grown in a lab that were "immortal," meaning that they do not die after a few cell divisions, and they could be used for conducting many experiments. This represented an enormous boon to medical and biological research.〔
The stable growth of HeLa enabled a researcher at the University of Minnesota hospital to successfully grow polio virus, enabling the development of a vaccine, and by 1954, Jonas Salk developed a vaccine for polio using these cells.〔 To test Salk's new vaccine, the cells were put into mass production in the first-ever cell production factory.
In 1955, HeLa cells were the first human cells successfully cloned.〔Puck TT, Marcus PI. A Rapid Method for Viable Cell Titration and Clone Production With Hela Cells In Tissue Culture: The Use of X-Irradiated Cells to Supply Conditioning Factors. Proc Natl Acad Sci U S A. 1955 Jul 15;41(7):432-7. URL: PNASJSTOR〕
Demand for the HeLa cells quickly grew. Since they were put into mass production, Lacks' cells have been used by scientists around the globe for "research into cancer, AIDS, the effects of radiation and toxic substances, gene mapping, and countless other scientific pursuits".〔 HeLa cells have been used to test human sensitivity to tape, glue, cosmetics, and many other products.〔 Scientists have grown some 20 tons of her cells,〔 and there are almost 11,000 patents involving HeLa cells.〔
==History==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「HeLa」の詳細全文を読む



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